Edition V09N02 | Year 2015 | Editorial Artigo Inédito | Pages 76 to 88
Objective: The aim of this study was to accomplish a literature review, based on currently available evidence, about the early periods of bone integration around endosseous implants with moderately rough and chemically modified surface (MRCM). Methods: The review was performed through an electronic survey via PubMed, using a combination of keywords, including: osseointegration, bone-to-implant contact, wettability, chemically modified surface and bone healing. Experimental in vitro studies, in animal models and in humans, covering physicochemical characteristics, biological mechanisms and initial histological events related to MRCM implant surface were considered. Results: Experimental studies report higher bone apposition and better bone anchorage to MRCM surfaces during early stages of bone healing in animal models. These experimental results were validated by prospective clinical studies, studies measuring implant stability with resonance frequency analysis, gene expression profiles and temporal histological studies in human models. Conclusion: Within the limitations of this MRCM surface study, it is suggested that high surface energy and increased wettability positively influence bone formation in the initial periods of bone repair.
Tabosa e Silva TP, Miranda CCL, Bucco Jr RLS, Tabosa e Silva TP, Sotto-Maior BS. The role of a moderately rough and chemically modified implant surface in an early loading protocol: a literature review. Dental Press Implantol. 2015 Apr-Jun;9(2):76-88. DOI: http://dx.doi.org/10.14436/2237-650X.9.2.076-088.oar